Solazyme's manufacturing miscues (2014), which weren't transparently communicated to investors. A careful analysis of the company's bioprocess metrics and downstream processing hurdles shed light on the problems. The company pivoted multiple times, changed its name to TerraVia, and eventually declared bankruptcy.

Intrexon's financial irregularities (2016), which were detailed in regulatory filings and tips from high-level employees. The company sent our founder a cease and desist letter in an attempt to stop his work. Shortly after an investigation from the U.S. Securities and Exchange Commission, Intrexon restructured into separate entities. The cease and desist is framed in our office.

Amyris' chronic mismanagement (2018+) and destruction of shareholder value. The synthetic biology pioneer underdelivered on financial targets for nearly a decade, abused partnerships, and misused Paycheck Protection Program (PPP) loans intended for small businesses. An article from Solt DB in late 2022 preceded the removal of the longtime CEO, bankruptcy, and delisting from the Nasdaq.

Ginkgo Bioworks' low foundry success rate (2022), which was discovered through a routine Freedom of Information Act (FOIA) request with the U.S. Securities and Exchange Commission. A document revealed the company had only commercialized three of over 21 flavor and fragrance ingredients from 2016 through 2022, which helps to explain the pivot toward pharma. An article from Solt DB in late 2022 detailed the findings.