Harmony Biosciences

HRMY

Last Price
07/17/26, 09:30 AM
 EDT
$
33.77
(
0.7
%)
(
+
0.7
%)
Margin of Safety
+
66.4
%
Modeled Fair Value
$
56.20
Allocation Group
Current Compounder
Modeled Fair Value
$3.299 billion
Allocation Tier

Harmony Biosciences got kicked in the deez by its fumbled patent infringement case against AET Pharma and came to its senses.

A long-time board director who helped start the company got booted out, while the CFO with hands so slippery he couldn't own a single share of the business got kicked to the curb. The neuroscience specialist also acquired exclusive global rights to the one piece of pitolisant intellectual property it didn't own, then turned around and filed a new patent infringement case against AET Pharma. That might be enough to make the whole debacle go away – after making a hefty cash payment to settle the dispute, anyway.

A massive settlement payment would be a fantastic investment considering it would protect over $325 million in annual operating cash flow for 2026, 2027, 2028, and at least half of 2029. Investors have reasons to doubt the company's ability to acquire assets that will change the narrative, but the renamed orexin-2 receptor (OX2R) agonist BP-205 could emerge as the golden ticket for a renewal. That's especially true considering the hype and multi-billion deals for similar assets from Takeda, Alkermes, and Centessa Pharmaceuticals.

If Harmony Biosciences announces a settlement of the patent infringement cases with AET Pharma, then shares would be expected to surge to or above the modeled fair value. The tricky thing is there are only a few months remaining until the district judge issues her ruling, which is expected in August. There's an uncomfortable level of risk involved, but the historical odds favor Harmony.

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Last Refined

February 25, 2026
The current model INCLUDES the following assets and assumptions:
The current model is based on operating metrics, including:

NOTE: The model doesn't account for a negative result from the patent litigation case with AET Pharma. A negative outcome would make Harmony Biosciences uninvestable and likely reset the stock price to below $10 per share.

Full-year 2026 operating metrics:

  • Full-year 2026 revenue of $997 million, representing an increase of 14.8% from sales of $868.453 million in 2025. Guidance expects $1.00 billion to $1.04 billion.
  • First-quarter 2026 revenue of $215 million, compared to $184.733 million in Q1 2025 and $243.776 million in Q4 2025. This reflects normal seasonality for Wakix in the opening frame of every calendar year.
  • Full-year 2026 gross margin of 75.5% compared to 77.2% in 2025 and 78.1% in 2024. Gross margin is highest in Q1 (>80%) and declines throughout the year, including the first second-quarter reading below 80% in the franchise's history.
  • Full-year 2026 operating expenses of $522 million, excluding patent litigation settlement payments, in-process R&D (IPR&D) expenses, and potential business development. This includes a quarterly average R&D spend of $57.5 million (an increase of 48% from 2025) and sales & marketing expenses of $40.0 million (an increase of 33.8% from 2025). All numbers include non-cash expenses.
  • Full-year 2026 operating cash flow of $235 million, including patent litigation expenses in Q1 that result in negative cash flow during the quarter. This excludes possible patent litigation expenses incurred after the bench trial in February 2026.
  • Full-year 2026 GAAP net income of $3.40 per share. This excludes patent litigation settlement payments, in-process R&D (IPR&D) expenses, and potential business development.

Wakix contributes $52.26 per share and Wakix GR contributes $3.94 per share. All other assets are excluded.

The current model EXCLUDES the following assets:

SEC Filings